#$%^&*AU2017203148B220180809.pdf#####ABSTRACT Pharmaceutical compositions in the form of a solid dosage form comprising: a) controlled release granules comprising a first quantity of nitazoxanide or an analogue thereof and b) immediate release granules comprising a second quantity of nitazoxanide or an analogue thereof are provided. Methods of reducing one or more side-effects associated with treatment with nitazoxanide or tizoxanide in a patient are also provided, the methods comprising administering to the patient a therapeutically effective amount of the pharmaceutical composition described above. Methods for increasing the bioavailability of nitazoxanide or an analogue thereof in a patient are also provided, the methods comprising administering to the patient a therapeutically effective amount of the pharmaceutical composition described above. Methods of extending absorption of nitazoxanide or an analogue thereof in a patient are also provided, the methods comprising administering to the patient a therapeutically effective amount of the pharmaceutical composition described above. 9044982_1 (GHMatters) P87871.AU.2
