#$%^&*AU2011221427B220130912.pdf#####Abstract A method for delivering a sedation drug comprising administering a drug to a patient while requesting the patent to respond to an instruction, monitoring a patients BIS values, brining the patient to a level of anesthesia where the patient fails to respond to the request within a 5 predetermined response time, and determining a BIS value that coincides with the level of anesthesia corresponding to the failure to response.