Gushchin, Aleksander Sergeevich,Yablonskiy, Petr Kazimirovich,Vinogradova, Tatiana Ivanovna,Batyunin, Gennady Andreevich,Zabolotnyh, Natalya Vyacheslavovna,Vasilieva, Svetlana Nikolaevna,Maligin, Alex
申请号：
AU2016265974
公开号：
AU2016265974A1
申请日:
2016.11.28
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
#$%^&*AU2016265974A120161215.pdf#####TUBERCULOSIS DRUG BASED ON 4-THIOUREIDO-IMINOMETHYLPYRIDINIUM PERCHLORATE: METHOD OF PREPARATION AND TREATMENT Abstract This invention relates to the field of chemical-pharmaceutical industry, specifically a new tuberculosis treatment that contains, as an active ingredient, 4-thioureidoiminomethylpridinium perchlorate at a therapeutically effective and safe level and pharmaceutically acceptable excipients. In addition, this treatment relates to a method of the preparation of the new drug, providing a high yield of the new treatment. The new treatment has a higher tuberculostatic activity (200 times as high) and lower toxicity (2.4 times as low), as compared to a prototype drug, and is stable during long-term storage. This medicament may be used for treating and preventing all forms of pulmonary and extrapulmonary TB by using the new treatment in combination with other TB drugs.
