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Tuberculosis drug based on 4-thioureido-iminomethylpyridinium perchlorate: method of preparation and treatment
专利权人:
Joint Stock Company “Pharmasyntez”
发明人:
Aleksander Sergeevich Gushchin,Tatiana Ivanovna Vinogradova,Petr Kazimirovich Yablonskiy,Gennady Andreevich Batyunin,Natalya Vyacheslavovna Zabolotnyh,Svetlana Nikolaevna Vasilieva,Alexey Vladimirovic
申请号:
US13657168
公开号:
US09750727B2
申请日:
2012.10.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention relates to the field of chemical-pharmaceutical industry, specifically a new tuberculosis treatment that contains, as an active ingredient, 4-thioureido-iminomethylpyridinium perchlorate at a therapeutically effective and safe level and pharmaceutically acceptable excipients. In addition, this treatment relates to a method of the preparation of the new drug, providing a high yield of the new treatment. The new treatment has a higher tuberculostatic activity (200 times as high) and lower toxicity (2.4 times as low), as compared to a prototype drug, and is stable during long-term storage. This medicament may be used for treating and preventing all forms of pulmonary and extrapulmonary TB by using the new treatment in combination with other TB drugs.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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