GUSHCHIN ALEKSANDER SERGEEVICH,VINOGRADOVA TATIANA IVANOVNA,YABLONSKIY PETR KAZIMIROVICH,BATYUNIN GENNADY ANDREEVICH,ZABOLOTNYH NATALYA VYACHESLAVOVNA,VASILIEVA SVETLANA NIKOLAEVNA,MALIGIN ALEXEY VLAD
申请号：
ZA201207189
公开号：
ZA201207189B
申请日:
2012.09.26
申请国别(地区):
ZA
年份:
2013
代理人:
摘要：
This invention relates to the field of chemical-pharmaceutical industry, specifically a new tuberculosis treatment that contains, as an active ingredient, 4-thioureido-iminomethylpyridinium perchlorate at a therapeutically effective and safe level and pharmaceutically acceptable excipients. In addition, this treatment relates to a method of the preparation of the new drug, providing a high yield of the new treatment. The new treatment has a higher tuberculostatic activity (200 times as high) and lower toxicity (2.4 times as low), as compared to a prototype drug, and is stable during long-term storage. This medicament may be used for treating and preventing all forms of pulmonary and extrapulmonary TB by using the new treatment in combination with other TB drugs.
