GUSHCHIN ALEKSANDER SERGEEVICH,VINOGRADOVA TATIANA IVANOVNA,YABLONSKIY PETR KAZIMIROVICH,BATYUNIN GENNADY ANDREEVICH,ZABOLOTNYH NATALYA VYACHESLAVOVNA,VASILIEVA SVETLANA NIKOLAEVNA,MALIGIN ALEXEY VLAD
申请号:
IN2222/MUMNP/2012
公开号:
IN2012MN02222A
申请日:
2012.09.20
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
This invention relates to the field of chemical- pharmaceutical industry specifically a new tuberculosis treatment that contains as an active ingredient 4-thioureido- iminomethylpyridinium perchlorate at a therapeutically effective and safe level and pharmaceutically acceptable excipients. In addition this treatment relates to a method of the preparation of the new drug providing a high yield of the new treatment. The new treatment has a higher tuberculostatic activity (200 times as high) and lower toxicity (2.4 times as low) as compared to a prototype drug and is stable during long-term storage. This medicament may be used for treating and preventing all forms of pulmonary and extrapulmonary TB by using the new treatment in combination with other TB drugs.