CHANG, CHENG HAO,张正澔,張正澔,LIN, I FENG,林宜锋,林宜鋒,HUANG, YUNG HSUAN,黄咏宣,黃詠宣
申请号：
TW102136158
公开号：
TWI482757B
申请日:
2013.10.07
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
The present disclosure provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein X is NH or O Y is NH or O Z is aryl group or heteroaryl group including N, O, P, or S and R1is H, halogen, C1-C6alkoxyl. The present disclosure also provides a pharmaceutical composition including the compound of formula (I) or the pharmaceutically acceptable salt thereof and a pharmaceutically acceptable vehicle. The present disclosure also provides use of the compound for preparing a medicament for treating a cell proliferative disorder.本發明提供一種式(I)之化合物或其藥學上可接受之鹽,其中X為NH或O;Y為NH或O;Z為芳基或含氮、氧、磷或硫之雜芳基;及R1為H、鹵基、或C1至C6之烷氧基。本發明更提供一種藥學組合物,包括式(I)之化合物或其藥學上可接受之鹽;及藥學上可接受之載體。本發明又提供此化合物用於製備治療細胞增生性病症的藥劑的用途。
