1. Application of 4 - [(2 - {(2R) -2 - [(1E, 3S) -4- (4-fluorophenyl) -3-hydroxy-1-buten-1-yl] -5-oxo-1- pyrrolidinyl} ethyl) thio] butanoic acid, its salt, its solvate or its clathrate complex with cyclodextrin to obtain an agent for the treatment of heart failure and / or symptom relief. 2. The use according to claim 1, wherein the heart failure is acute heart failure or chronic heart failure. 3. The use of claim 1, wherein the heart failure is diastolic heart failure. 4. The use according to any one of paragraphs. 1-3, where the symptom is stagnation, shortness of breath, shortness of breath, anxiety, decreased urine volume, swelling of the extremities and / or enlarged liver. 5. Application 4 - [(2 - {(2R) -2 - [(1E, 3S) -4- (4-fluorophenyl) -3-hydroxy-1-buten-1-yl] -5-oxo-1-pyrrolidinyl} ethyl) thio] butanoic acid, its salt, its solvate or its clathrate complex with cyclodextrin for the preparation of a heart failure treatment that changes the positive dP / dt peak and the negative dP / dt peak of a mammal having a pathological heart failure state, where the ratio of change the negative peak dP / dt calculated from the values before and after the administration of the drug is greater than the ratio of the change in the positive peak dP / dt. 6. The use of claim 5, which is a compound for the treatment of diastolic heart failure and / or symptom relief. Application 4 - [(2 - {(2R) -2 - [(1E, 3S) -4- (4-fluorophenyl) -3-hydroxy-1-buten-1-yl] -5-oxo-1-pyrrolidinyl} ethyl) thio] butanoic acid, its salt, its solvate or its clathrate complex with cyclodextrin to obtain an agent for improving cardiac survival1. Применение 4-[(2-{(2R)-2-[(1E,3S)-4-(4-фторфенил)-3-гидрокси-1-бутен-1-ил]-5-оксо-1-пирролидинил}этил)тио]бутановой кислоты, ее соли, ее сольвата или ее клатратного комплекса с циклодекстрином для получения средства для лечения сердечной недостаточности и/или облегчения симптома.2. Применение по п. 1, где сердечная недостаточность представляет собой острую серд
