Hyoung-jin PARK;JBK NATURAL MEDICINE INSTITUTE;MUSHMED CO., LTD.
发明人:
Hyoung-jin PARK,Bong-gun JANG
申请号:
US15317752
公开号:
US20170106035A1
申请日:
2015.06.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A composition includes a black chokeberry extract and at least one of a thistle extract, a black hoof mushroom extract and a mixture thereof. The composition is effective in preventing and treating non-alcoholic fatty liver disease caused by accumulation of fat in the liver due to excessive intake of nutrients or metabolic syndrome regardless of alcohol intake. The composition can improve the increase in liver weight, accumulation of neutral fat in the liver, increase in serum ALT concentration, and reduction of liver SOD activity and total antioxidant activity of the liver, in experimental animals grown with a high-fat diet. Since the fatty liver disease caused by a high-fat diet in experimental animals shows similar pathological and immunological manifestations to human non-alcoholic fatty liver disease, the composition can be provided as a pharmaceutical agent or health supplement food used to prevent and treat non-alcoholic fatty liver disease.