Heat Inactivated Poxvirus Improves Vaccination Results

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专利权人:

发明人:

Bertram Jacobs,Trung Huynh,Negin Blattman,Keith Dumbell

申请号：

US15125024

公开号：

US20170021009A1

申请日:

2015.03.10

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Compositions including a heat-inactivated poxvirus, such as vaccinia virus, that induces one or more interferons in a vaccine recipient. The compositions may further include one or more live vaccine vectors and non-replicating vaccine components. Methods of vaccine preparation and administration including a heat-inactivated poxvirus, such as vaccinia virus, improve vaccine immunogenicity and safety.

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