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WAYS TO INCREASE VACCINE EFFICIENCY BY INTRODUCING IL-4R ANTAGONIST
专利权人:
ИНК. (US);РИДЖЕНЕРОН ФАРМАСЬЮТИКАЛЗ
发明人:
ПЕРСЕЛЛ НГАМБО, Лайза (US),ГРЭХЕМ, Нейл (US),МЕРФИ, Эндрю Дж. (US),ЭВАНС, Роберт (US)
申请号:
RU2018133011
公开号:
RU2018133011A
申请日:
2017.02.17
申请国别(地区):
RU
年份:
2020
代理人:
摘要:
The present invention provides methods for enhancing the efficacy and/or safety of a vaccine. In certain embodiments, the invention provides methods to increase or potentiate the immune response to a vaccine in a subject in need thereof. The methods of the present invention comprise administering to a subject in need thereof an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody in combination with said vaccine. In certain embodiments, the methods of the present invention are used to afford enhanced protection to an infectious disease such as whooping cough.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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