CYCLOHEXÉNYLES COMME MODULATEURS DE L'ACTIVITÉ DES RÉCEPTEURS DE CHIMIOKINES

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

申请号：

EP09790359.5

公开号：

EP2318352B1

申请日:

2009.07.14

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present application describes modulators of MCP-1 or CCR-2 of formula (I), or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein T, W, X, Y, Z, R1, R2, R4 and R6, are defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I), are disclosed.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/