Percy H. Carter;Gregory D. Brown;Douglas G. Batt;George V. De Lucca;Rui-Qin Liu;Feng Qiu
发明人:
Percy H. Carter,Gregory D. Brown,George V. De Lucca,Douglas G. Batt,Rui-Qin Liu,Feng Qiu
申请号：
US13003780
公开号：
US08507559B2
申请日:
2009.07.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present application describes modulators of MCP-1 or CCR-2 of formula, (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein T, W, X, Y, Z, R1, R2, R4 and R6, are defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula, (I) are disclosed.
