MODULATEURS CYCLIQUES DE L'ACTIVITÉ DE RÉCEPTEURS DE CHIMIOKINES

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

申请号：

EP07843699.5

公开号：

EP2061759B1

申请日:

2007.10.03

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present application describes modulators of MIP-1&alpha； or CCR-1 of formula (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein n, ring A, T, V, X, R1, R2 and R8, are defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I) are disclosed.

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