Percy H. Carter;Ian K. Mangion;Andrew J. Tebben;Jingwu Duan
发明人:
Ian K. Mangion,Percy H. Carter,Jingwu Duan,Andrew J. Tebben
申请号:
US13576706
公开号:
US20120295899A1
申请日:
2011.02.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present application describes modulators of MCP-1 or CCR-2 of formulaor stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein m, n, W, X, R1 and R6, are defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I) are disclosed.