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Chromene modulators of chemokine receptor activity
专利权人:
Douglas G. Batt
发明人:
Douglas G. Batt
申请号:
US13003777
公开号:
US08759390B2
申请日:
2009.07.14
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present application describes modulators of MCP-1 or CCR-2 of formula (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W1, W2, W3, Y, Z, R2, R3, R3′ and R4, are defined in the specification. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I) are disclosed.
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