Detection of loss of the wild-type p53 gene

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专利权人:

发明人:

申请号：

EP90301817.4

公开号：

EP0390323B2

申请日:

1990.02.20

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Methods and kits are provided for assessing mutations and/or loss of the p53 gene in human tumors. Both deletion mutations and point mutations in p53 are observed in the same human tumor cells and these mutations are clonal within the cells of the tumor. Loss of wild-type p53 genes is responsible for neoplastic progression.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/