HNF4G-RSPO2 FUSION GENE AND USE THEREOF IN TREATMENT OF CANCER

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专利权人:

Crown Bioscience; Inc. (Taicang)

发明人:

CAI, Jie,LI, Henry

申请号：

EP15772589

公开号：

EP3126521A4

申请日:

2015.04.03

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

A method for predicting the responsiveness of a cancer cell to an MEK inhibitor, comprising detecting the presence of at least one mutation in one or more genes selected from the group consisting of ADAM12, COL14A1, TNN, and TP53, in the cancer cell, by contacting a nucleic acid sample derived from the cancer cell with at least one oligonucleotide which allows specific detection of the mutation wherein presence of mutation in ADAM12, COL14A1, TNN, TP53 and/or any combination thereof is indicative of decreased responsiveness of the cancer cell to the ERK inhibitor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/