PEPTIDE ABLE TO DISRUPT THE PROTEIN COMPLEX BETWEEN THE HIS273 MUTADED P53 PROTEIN AND THE ONCOSUPPRESSIVE P73 PROTEIN IN TUMOR CELLS AND THERAPEUTIC USES THEREOF
Gennaro Citro,Giovanni Blandino,Sabrina Strano,Silvia Di Agostino
申请号:
US13319682
公开号:
US20120237614A1
申请日:
2010.05.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention concerns a SIMP peptide (Short-interfering mutant p53 peptides) suitable to disrupt the protein complexes within tumour cells resulting from m-p53 and p73 proteins selectively in tumours wherein m-p53 contains His273 mutation.