THIAZOLES A SUBSTITUTION AMIDE UTILISES COMME MODULATEURS DE ROR.GAMMA.T

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专利权人:

JANSSEN PHARMACEUTICA NV

发明人:

VENKATESAN, HARIHARAN,TANIS, VIRGINIA,URBANSKI, MAUD,WANG, AIHUA,KUMMER, DAVID,STEENECK, CHRISTOPH,GEGE, CHRISTIAN,KINZEL, OLAF,KLEYMANN, GERALD,HOFFMANN, THOMAS,GOLDBERG, STEVEN,FOURIE, ANNE M.,XUE,

申请号：

CA2965518

公开号：

CA2965518A1

申请日:

2015.10.30

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R5, A1, A2, and ? are defined in the specification. The invention also comprises a compound of Formula I for use in a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a compound for use in a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/