Steven Goldberg,Hariharan Venkatesan,Virginia Tanis,Maud Urbanski,Aihua Wang,David Kummer,Christoph Steeneck,Christian Gege,Olaf Kinzel,Gerald Kleymann,Thomas Hoffmann,Anne M. Fourie,Xiaohua Xue
申请号：
US14927502
公开号：
US09845319B2
申请日:
2015.10.30
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention comprises compounds of Formula I.wherein:R1, R2, R3, R5, A1, A2, andare defined in the specification.The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein the syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
