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VALSARTAN-AMLODIPINE COMPOUND SOLID PREPARATION AND PREPARATION METHOD THEREFOR
专利权人:
发明人:
Wenhui LIN,Kepan GAO,Ling FU,Li YING,Chen WU,Haitao ZHAO
申请号:
US14409719
公开号:
US20150352048A1
申请日:
2013.06.21
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a compound solid preparation and the preparation method therefor and specifically relates to a valsartan-amlodipine compound solid preparation and the preparation method therefor. The valsartan-amlodipine compound solid preparation comprises valsartan particles and an amlodipine premix. The valsartan particles are prepared by preparing wet valsartan particles from a mixture obtained by mixing valsartan and a pharmaceutic adjuvant with an ethanol aqueous solution as a wetting agent and drying the wet valsartan particles. The amlodipine premix is prepared by mixing amlodipine and a pharmaceutic adjuvant. The valsartan-amlodipine compound solid preparation according to the present invention and the preparation method thereof can prevent the two main ingredients, amlodipine and valsartan, from interfering each other, and the preparation method is relatively simple and suitable for large-scale industrial production.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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