Disclosed is a method of more accurately stimulating a living body and an apparatus using the method. The method includes determining targeted bio-information, deriving bio-stimulation information required to achieve the targeted bio-information using complicated time space data indicative of bio-responses interacting at a plurality of different positions in response to bio-stimulation composed of pieces of time-series data having a specific frequency, and applying a stimulation signal to the living body in response to the derived bio-stimulation information. The method is advantageous in that it can derive a systematic algorithm between bio-related information and stimulation information so that more accurate and safely stimulation is made upon applying bio-stimulation based on acquired bio-related information, can minimize a process of trial and error using a systematic algorithm, and can more accurately stimulate a living body by exactly determining a specific target stimulation position.
