The present invention describes the improvements due to alternated actuation cycles to reduce the delivery errors related to the pumping chamber elasticity the actuator relaxation or hysteresis. The method actuates a pumping device with an optimal driving voltage profile wherein the pumping device comprises a pumping chamber including a pumping membrane and a voltage controlled actuator connected to said membrane the movement of said membrane being defined by three positions namely a rest a bottom and a top position. The method includes the actuation of the membrane with a pumping pattern including at least two different cycles : Cycle A : rest bottom rest top rest Cycle B : rest top rest bottom rest. The invention also relates to a device to carry out the method.
