PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

LE TIRAN, ARNAUD,GRILLOT, ANNE-LAURE,CHARIFSON, PAUL, S.,BENNANI, YOUSSEF, LAAFIRET,O'DOWD, HARDWIN,PEROLA, EMANUELE,ODOWD, HARDWIN

申请号：

SG2013053426

公开号：

SG191946A1

申请日:

2012.01.13

申请国别(地区):

SG

年份:

2013

代理人:

摘要：

The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti¬ bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.

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