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PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS
专利权人:
VERTEX PHARMACEUTICALS INCORPORATED
发明人:
LE TIRAN ARNAUD,GRILLOT ANNE-LAURE,CHARIFSON PAUL S,BENNANI YOUSSEF LAAFIRET,O'DOWD HARDWIN,PEROLA EMANUELE,ODOWD HARDWIN
申请号:
ZA201305233
公开号:
ZA201305233B
申请日:
2013.07.11
申请国别(地区):
ZA
年份:
2014
代理人:
摘要:
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.
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