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Gyrase and topoisomerase IV inhibitors
专利权人:
Emanuele Perola;Arnaud Le Tiran;Hardwin O'Dowd;Paul S. Charifson;Anne-Laure Grillot;Yousef Laafiret Bennani
发明人:
Arnaud Le Tiran,Anne-Laure Grillot,Paul S. Charifson,Yousef Laafiret Bennani,Hardwin O'Dowd,Emanuele Perola,Hardwin ODowd
申请号:
US13349789
公开号:
US08481551B2
申请日:
2012.01.13
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a compound of formula (I)or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.
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