compound, pharmaceutical composition, method for inhibiting bacterial DNA gyrase and / or bacterial iv topoisomerase, for producing an antibacterial effect, and for treating a bacterial infection in a warm-blooded animal, and use of a compound
- 专利权人:
- ASTRAZENECA AB
- 发明人:
- BRIAN SHERER,FEI ZHOU
- 申请号:
- BRPI0913583
- 公开号:
- BRPI0913583A2
- 申请日:
- 2009.06.04
- 申请国别(地区):
- BR
- 年份:
- 2015
- 代理人:
- 摘要:
- Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
- 来源网站:
- 中国工程科技知识中心
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- SOLID FORMS OF GYRASE INHIBITOR (R)-1-ETHYL-3-[6-FLUORO-5-[2-(1-HYDROXY-1-METHYL-ETHYL)PYRIMIDIN-5-YL]-7-(TETRAHYDROFURAN-2-YL)-1H-BENZIMIDAZOL-2-YL]UREA
- Solid forms of gyrase inhibitor (R)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl) pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-yl]urea
- SOLID FORMS OF GYRASE INHIBITOR (R)-1-ETHYL-3-[6-FLUORO-5-[2-(1-HYDROXY-1-METHYL-ETHYL) PYRIMIDIN-5-YL]-7-(TETRAHYDROFURAN-2-YL)-1H-BENZIMIDAZOL-2-YL]UREA
- PROCESS OF MAKING GYRASE AND TOPOISOMERASE IV INHIBITORS
- COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT OF THE SAME, PHARMACEUTICAL COMPOSITION, BACTERIAL DNA GYRASE AND / OR TOPOISOMERASE IV INHIBITION METHODS IN A HOT BLOOD ANIMAL, PRODUCING AN ANTIBANTER EFFECT OF ANTI BLOOD OF ANTI BLOOD BACTERIAL INFECTION IN A HOT BLOOD ANIMAL, AND USE OF A PHARMACEUTICALLY ACCEPTABLE COMPOUND OR SALT