Arnaud Le Tiran,Anne-Laure Grillot,Paul S. Charifson,Youssef Laafiret Bennani,Hardwin O'Dowd,Emanuele Perola,Hardwin ODowd
申请号:
US13908593
公开号:
US08969359B2
申请日:
2013.06.03
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a compound of formula (I)or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.