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DERIVE BIARYLE ET MEDICAMENT LE CONTENANT
专利权人:
LTD.;KAKEN PHARMACEUTICAL CO.
发明人:
WATANABE, ATSUSHI,SATO, YUUKI,OGURA, KEIJI,TATSUMI, YOSHIYUKI
申请号:
CA2997537
公开号:
CA2997537A1
申请日:
2016.09.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Provided is a compound showing excellent antifungalactivity against Trichophyton fungus, which is a majorcausative microorganism of superficial mycosis, and higheffectiveness on diseases caused by Trichophyton fungi. Abiaryl derivative represented by the formula (I) or a saltthereof:(see formula I)wherein ring A is an optionally substituted phenyl, or anoptionally substituted 5- or 6-membered ring heteroaryl (ring Amay be further condensed to form an optionally substitutedfused ring); Q is CH2, C=O, NH, O, S or the like; X1, X2 and X3are CR1 or N; Y is CH or N; Z is CR2b or N; R2a and R2b are eacha hydrogen atom, a halogen atom, an optionally substitutedC1-C6 alkyl group, a C1-C6 haloalkyl group or the like; R2a and R2bmay form, together with carbon atoms bonded thereto, anoptionally substituted carbocycle, or an optionally substitutedheterocycle.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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