DERIVE D'AMINOPYRAZINE ET MEDICAMENT CORRESPONDANT

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专利权人:

NIPPON SHINYAKU CO.; LTD.

发明人:

FUJIHARA, HIDETAKA,ASAKI, TETSUO,HORI, KATSUTOSHI,NAITO, HARUNA

申请号：

CA2751695

公开号：

CA2751695C

申请日:

2010.02.05

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

A compound represented by general formula [1]satisfying the following (I) or (II), or a pharmaceuticallyacceptable salt of the compound.(see formula 1)(I) X is CH or N； R1 is a halogen atom； and R2 is H, a halogenatom, CN, [2], [3], [8], [9], an -O-alkyl, an -O-(saturatedring), etc.[2]: -C(R C )(R E) (R E) {R C to R E each are H, an alkyl, etc.}[3]: -N(R F)( R G) {R E and R G each are H, OH, amino, a(hetero)aryl, etc.}[8]: -C(=O)R L {R L is an alkyl, OH, an alkoxy, amino, etc.}[9]: a (substituted)phenyl；(II) X is >；C-C(=O)R B (R B is a (substituted)amino, an alkoxy,OH, etc.)；R1 is a halogen atom； R2 is H； R3 is H or OH； and R3 and R4 eachis H or an alkyl.

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