The present invention provides a compound of Formula(I):(see formula I)wherein R1, R2, R3 and R4 are each independently selectedfrom a hydrogen atom, an optionally substituted C1-C6 alkylgroup, an optionally substituted C7-C14 aralkyl groupand -C(=O)Rx； Rx represents an optionally substituted C1-C6alkyl group, an optionally substituted aryl group, anoptionally substituted heteroaryl group, an optionallysubstituted C1-C6 alkoxy group or -NReRf； Ar1 represents anoptionally substituted aromatic carbocyclic ring or anoptionally mono-substituted aromatic heterocyclic ring； Qrepresents -(CH2)m- (L)p- or -(L)p- (CH2)m-； m represents aninteger selected from 0 to 2, n represents an integer selectedfrom 1 and 2, and p represents an integer selected from 0 and1； L represents -O-, -S- or -NR5-； and A represents anoptionally substituted aryl group or an optionally substitutedheteroaryl group, a prodrug thereof and a pharmaceuticallyacceptable salt thereof, as well as a pharmaceuticalpreparation or pharmaceutical composition comprising such acompound.
