MANORANJAN PANDA,MALLIKARJUNA RAO METTU,SHILPA MAHESHWARAPPA HOLEHATTI,RAJESH ONKARDAS BORA,SRINIVASAN THANGATHIRUPATHY,SELVAKUMAR KUMARAVEL,GAN WANG,ZHONG YANG,VAN N. NGUYEN,MAKONEN BELEMA,ROBERT A.
申请号：
ARP160101147
公开号：
AR104388A1
申请日:
2016.04.22
申请国别(地区):
AR
年份:
2017
代理人:
摘要：
Claim 1: a compound characterized by the formula (1), which includes acceptable salts of this from the point of view of Pharmaceuticals, where: r\u00b9\u1d43 and r\u00b9\u1d47 are selected, each independently Hydrogen, alkyl, arylalkyl ariloxiarilo, cycloalkyl, aryl, heterociclilo,,Heterociclilalquilo and - alkyl Co (r\u02e3), where the heterociclilo is linked to the Molecule of origin through a carbon Atom, and also where the groups r\u00b9\u1d43 and r\u00b9\u1d47 are replaced with 0 - 4 selected groups regardless of alquenilo, alcoxicarbonilo, alkyl, alkoxy, Quiltioxi, Benzyloxy, alquinilo, aryl, arylalkyl carboxylic acid, cyano, ariloxi, Halo, haloalquilo,Haloalcoxi, heterociclilo, heterociclilalquilo, Hydroxy, hidroxialquilo, tioxi, ch\u2082nh\u2082 heteroaryl alkyl -, -, alkyl - CO, CO (r\u02e3) - (r\u02b8) \u2082, - nhcon (r\u02b8) \u2082 - nhco - nhco\u2082 alkyl, alkyl, - - - - och\u2082 nhso\u2082 alkyl, aryl, - SO\u2082 SO\u2082 - N - alkyl - (r\u02b8) and \u2082 - SO\u2082 - r\u00b9\u1d43 and heterociclilo or R\u00b9\u1d47 along with the nitrogen Atom to which they are UnitedForm a heterocycle was replaced with 0 - 4 selected groups regardless of alquenilo, alkyl, alkoxy, alcoxicarbonilo, alquiltioxi, Benzyloxy, alquinilo, aryl carboxylic acid, cyano, Halo, haloalquilo, haloalcoxi, Hydroxy, hidroxialquilo, tioxi ch\u2082nh\u2082 alkyl -, -, - heteroar ILO, alkyl - CO, CO (r\u02e3) - (\u2082 r\u02b8), - N (r\u02b8) with \u2082 (r\u02b8), N (r\u02b8) - CO - (N - alkyl, alkyl Carbon r\u02b8),N - (r\u02b8) SO\u2082 alkyl, aryl och\u2082 - - - - - - SO\u2082 SO\u2082 alkyl, N - (r\u02b8) \u2082 and SO\u2082 - heterociclilo R\u00b2 is H, alkyl or cycloalkyl c\u2081\u208b\u2084 c\u2083\u208b\u2084 r\u00b3 is H, alkyl or cycloalkyl c\u2081\u208b\u2084 c\u2083\u208b\u2084 r\u2074 is H, alkyl, aryl, c\u2085\u208b\u2081\u2080 bicicloalquilo, c\u2083\u208b\u2087 cycloalkyl or heteroa Rilo with 0 - 4 selected groups regardless of alquenoxi, alquenilo, alkyl, alkoxy, a
