Stefanie Keil,Matthias Urmann,Wolfgang Wendler,Maike Glien,Hans Matter,Harry Randall Munson, Jr.
申请号:
US12997095
公开号:
US08716317B2
申请日:
2009.05.22
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to Sulfonamides with heterocycle and oxadiazolone headgroup and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARalpha agonist activity. What is described are compounds of the formula (I), in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.