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Annelated pyrrolidin sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
专利权人:
Ulrike Wendler;Stefanie Keil;Wolfgang Wendler;Hans Matter;Eugen Falk;Maike Glien;Matthias Urmann
发明人:
Stefanie Keil,Matthias Urmann,Wolfgang Wendler,Ulrike Wendler,Maike Glien,Hans Matter,Eugen Falk
申请号:
US12996784
公开号:
US08329725B2
申请日:
2009.05.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to annelated pyrrolidin sulfonamides with oxadiazolone headgroup and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARalpha agonist activity. What is described are compounds of the formula (I), in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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