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Annelated N-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
专利权人:
Hans Matter;Eugen Falk;Maike Glien;Matthias Urmann;Ulrike Wendler;Stefanie Keil
发明人:
Stefanie Keil,Matthias Urmann,Wolfgang Wendler,Maike Glien,Hans Matter,Eugen Falk
申请号:
US12996692
公开号:
US08946212B2
申请日:
2009.05.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Annelated N-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals The invention relates to annelated N-heterocyclic sulfonamides with oxadiazolone headgroup and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARalpha agonist activity. What is described are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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