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Sulfonyl-phenyl-2H-[1,2,4]oxadiazol-5-one derivatives, processes for their preparation and their use as pharmaceuticals
专利权人:
Hans-Ludwig Schaefer;Karl Schoenafinger;Stefanie Keil;Wolfgang Wendler;Eugen Falk;Maike Glien;Matthias Urmann
发明人:
Stefanie Keil,Matthias Urmann,Karl Schoenafinger,Wolfgang Wendler,Maike Glien,Hans-Ludwig Schaefer,Eugen Falk
申请号:
US12480974
公开号:
US08173674B2
申请日:
2009.06.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to sulfonyl-phenyl-oxadiazolones and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARgamma agonist activity.What are described are compounds of the formula I,in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.
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