您的位置: 首页 > 农业专利 > 详情页

2,6-methane-3-benzazocine substituted at position 8 and substituted morphinan at position 3 as opioid receptor ligands
专利权人:
RENSSELAER POLYTECHNIC INSTITUTE
发明人:
Wentland, Mark P.
申请号:
ES08004779
公开号:
ES2572332T3
申请日:
2001.10.31
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Compound of formula: ** Formula ** where ** Formula ** A is chosen from Q is S R2 and R2a are both hydrogen or R2 and R2a together are>; = O; R3 is selected from hydrogen, an alkyl group of 1 to 6 carbon atoms, alkenyl, aryl, heterocyclyl, benzyl and hydroxyalkyl; R4 is selected from hydrogen, hydroxyl, amino, an alkoxy group of 1 to 4 carbon atoms, alkyl of 1 to 20 carbons and alkyl of 1 to 20 carbons substituted with hydroxyl or carbonyl; R5 is an alkyl group of 1 to 6 carbon atoms; R6 is an alkyl group of 1 to 6 carbon atoms; R7 is hydrogen; or R4, R5, R6 and R7 together can form a ring, said ring optionally having an additional substitution; and R16 is selected from hydrogen and NH2.Compuesto de fórmula:**Fórmula** donde**Fórmula** A se elige de Q es S R2 y R2a son ambos hidrógeno o R2 y R2a juntos son >;=O; R3 se elige entre hidrógeno, un grupo alquilo de 1 a 6 átomos de carbono, alquenilo, arilo, heterociclilo, bencilo e hidroxialquilo; R4 se elige entre hidrógeno, hidroxilo, amino, un grupo alcoxi de 1 a 4 átomos de carbono, alquilo de 1 a 20 carbonos y alquilo de 1 a 20 carbonos sustituido con hidroxilo o carbonilo; R5 es un grupo alquilo de 1 a 6 átomos de carbono; R6 es un grupo alquilo de 1 a 6 átomos de carbono; R7 es hidrógeno; o R4, R5, R6 y R7 juntos pueden formar un anillo, teniendo dicho anillo opcionalmente un sustitución adicional; y R16 se selecciona entre hidrógeno y NH2.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充