METHODS FOR TREATING CANCER USING ANTAGONISTS BINDING THE PD-1 AXIS AND TIGIT INHIBITORS

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专利权人:

ДЖЕНЕНТЕК; ИНК. (US)

发明人:

ГРОГАН, Джейн (US),ДЖОНСТОН, Роберт, Дж. (US),ИРВИНГ, Брайан (US),ХЭКНИ, Джейсон (US),ЮЙ, Синь (US),ИТОН, Дэн (US),БОУЛЗ, Кристин (US),КОМПС-АГРАР, Летисия (US)

申请号：

RU2019129525

公开号：

RU2019129525A

申请日:

2014.07.16

申请国别(地区):

RU

年份:

2019

代理人:

摘要：

The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.

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