Jane GROGAN,Robert J. JOHNSTON,Bryan IRVING,Jason HACKNEY,Xin YU,Dan EATON,Kristin BOWLES,Laetitia COMPS-AGRAR
申请号:
US15239569
公开号:
US20170044256A1
申请日:
2016.08.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.