ГРОГАН Джейн (US),ДЖОНСТОН Роберт Дж. (US),ИРВИНГ Брайан (US),ХЭКНИ Джейсон (US),ЮЙ Синь (US),ИТОН Дэн (US),БОУЛЗ Кристин (US),КОМПС-АГРАР Летисия (US)
申请号:
RU2016104880
公开号:
RU2016104880A
申请日:
2014.07.16
申请国别(地区):
RU
年份:
2017
代理人:
摘要:
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.