Jane Grogan,Robert J. Johnston,Bryan Irving,Jason Hackney,Xin Yu,Dan Eaton,Kristin Bowles,Laetitia Comps-Agrar
申请号：
US14333375
公开号：
US09873740B2
申请日:
2014.07.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.
