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Substituted pyrrolidine carboxamide compounds
专利权人:
Inc.;Epizyme
发明人:
Foley, Megan Alene Cloonan,Kuntz, Kevin Wayne,Mitchell, Lorna Helen,Munchhof, Michael John,Harvey, Darren Martin
申请号:
AU2015315177
公开号:
AU2015315177A1
申请日:
2015.09.09
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present disclosure provides pyrrolidine carboxamide compounds having Formula I and the pharmaceutically acceptable salts and solvates thereof, wherein A, B, X, Y, and Z are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of SMYD proteins such as SMYD3 or SMYD2. Compounds of the present disclosure are especially useful for treating cancer.
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中国工程科技知识中心
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