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Nanoparticle-based liver-targeting therapy and imaging
专利权人:
Midatech Limited
发明人:
Barrientos, Africa Garcia,Dominguez, Esther de Torres
申请号:
AU2016299336
公开号:
AU2016299336A1
申请日:
2016.07.25
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The invention provides a nanoparticle comprising: a core comprising a metal and/or a semiconductor; and a plurality of ligands covalently linked to the core, wherein said ligands comprise: at least one liver-targeting ligand; at least one payload ligand comprising a bioactive agent; and at least one dilution ligand comprising a carbohydrate. Also provided are pharmaceutical compositions comprising the nanoparticles, medical uses thereof, including in the treatment and imaging of liver cancers, and processes for the production of the nanoparticles.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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