Barrientos, Africa Garcia,Dominguez, Esther de Torres
申请号:
AU2016299336
公开号:
AU2016299336A1
申请日:
2016.07.25
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The invention provides a nanoparticle comprising: a core comprising a metal and/or a semiconductor; and a plurality of ligands covalently linked to the core, wherein said ligands comprise: at least one liver-targeting ligand; at least one payload ligand comprising a bioactive agent; and at least one dilution ligand comprising a carbohydrate. Also provided are pharmaceutical compositions comprising the nanoparticles, medical uses thereof, including in the treatment and imaging of liver cancers, and processes for the production of the nanoparticles.