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THERAPIES ET IMAGERIE CIBLANT LE FOIE A BASE DE NANOPARTICULES
专利权人:
MIDATECH LIMITED
发明人:
BARRIENTOS, AFRICA GARCIA,DOMINGUEZ, ESTHER DE TORRES
申请号:
CA2993278
公开号:
CA2993278A1
申请日:
2016.07.25
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention provides a nanoparticle comprising: a core comprising a metal and/or a semiconductor; and a plurality of ligands covalently linked to the core, wherein said ligands comprise: at least one liver-targeting ligand; at least one payload ligand comprising a bioactive agent; and at least one dilution ligand comprising a carbohydrate. Also provided are pharmaceutical compositions comprising the nanoparticles, medical uses thereof, including in the treatment and imaging of liver cancers, and processes for the production of the nanoparticles.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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