BARRIENTOS, AFRICA GARCIA,DOMINGUEZ, ESTHER DE TORRES
申请号：
CA2993278
公开号：
CA2993278A1
申请日:
2016.07.25
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The invention provides a nanoparticle comprising: a core comprising a metal and/or a semiconductor； and a plurality of ligands covalently linked to the core, wherein said ligands comprise: at least one liver-targeting ligand； at least one payload ligand comprising a bioactive agent； and at least one dilution ligand comprising a carbohydrate. Also provided are pharmaceutical compositions comprising the nanoparticles, medical uses thereof, including in the treatment and imaging of liver cancers, and processes for the production of the nanoparticles.
