Yan Qiu;Anthony Sandrasagra;Vincent Frans Maria Segers
发明人:
Vincent Frans Maria Segers,Anthony Sandrasagra,Yan Qiu
申请号:
US13029891
公开号:
US09308277B2
申请日:
2011.02.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention features mutant stromal cell derived factor-1 (SDF-1) peptides that have been mutated to make them resistant to digestion by, for example, the proteases dipeptidyl peptidase IV (DPPIV), matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), leukocyte elastase, cathepsin G, carboxypeptidase M, and carboxypeptidase N, but which retain chemoattractant activity.