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Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived Factor-1
专利权人:
Mesoblast International Sarl
发明人:
Sandrasagra, Anthony,Wu, Weitao
申请号:
AU2012268078
公开号:
AU2012268078B2
申请日:
2012.06.06
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention features methods for treating or ameliorating tissue damage using intravenous administration of compositions that include stromal cell derived factor-1 (SDF-1) peptides or mutant SDF-1 peptides that have been mutated to make them resistant to protease digestion, but which retain chemoattractant activity. Systemic delivery, and specifically intravenous ("IV") delivery, of SDF-1 and protease resistant SDF-1 mutants is very effective for the treatment of tissue damage.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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