Method for repairing tissue damage using protease resistant mutants of stromal cell-derived factor-1

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专利权人:

メソブラスト インターナショナル エスエイアールエル

发明人:

サンドラサグラ アンソニー,ウー ウェイタオ

申请号：

JP2014514581

公开号：

JP6145089B2

申请日:

2012.06.06

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The present invention features methods for treating or ameliorating tissue damage using intravenous administration of compositions that include stromal cell derived factor-1 (SDF-1) peptides or mutant SDF-1 peptides that have been mutated to make them resistant to protease digestion, but which retain chemoattractant activity. Systemic delivery, and specifically intravenous (“IV”) delivery, of SDF-1 and protease resistant SDF-1 mutants is very effective for the treatment of tissue damage.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/