스티븐스, 피터 제이.,스틸웰, 레지날드,사우다드, 매튜,사마니에고, 아드리안 씨.,마뉴엘, 찰스
申请号:
KR1020187029640
公开号:
KR1020180127640A
申请日:
2017.03.16
申请国别(地区):
KR
年份:
2018
代理人:
摘要:
Provided in this disclosure are various composite grafts having a trabecular synthetic scaffold with voids defined in at least a portion of the scaffold and a biological component positioned in at least some of the voids of the scaffold. The grafts may be osteogenic, chondrogenic, osteochondrogenic, or vulnerary in nature. Also provided are methods of using the composite grafts to treat a tissue defect in a subject. Methods of manufacturing are also provided. Grafts are manufactured by additive manufacturing. Agitation may be used to combine composite grafts with additional biological component.