Stevens, Peter J.,Stilwell, Reginald,Southard, Matthew,Samaniego, Adrian C.,Manuele, Charles
申请号:
AU2017232902
公开号:
AU2017232902A1
申请日:
2017.03.16
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Provided in this disclosure are various composite grafts having a trabecular synthetic scaffold with voids defined in at least a portion of the scaffold and a biological component positioned in at least some of the voids of the scaffold. The grafts may be osteogenic, chondrogenic, osteochondrogenic, or vulnerary in nature. Also provided are methods of using the composite grafts to treat a tissue defect in a subject. Methods of manufacturing are also provided. Grafts are manufactured by additive manufacturing. Agitation may be used to combine composite grafts with additional biological component.